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Exploring molecular interactions between polypeptide conjugates and protein targets: Manipulating affinity by chemical modifications
In this thesis molecular interactions between polypeptide conjugates and protein targets were investigated. Polypeptides were derivatized with small organic molecules, peptides and oligonucleotides. New strategies were developed with the aim to increase affinities for proteins of biological interest.
Alexandra Balliu's dissertation
Alexandra Balliu, Organic Chemistry, defends her PhD Thesis entitled "Exploring molecular interactions between polypeptide conjugates and protein targets: Manipulating affinity by chemical modifications".