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The subject of this thesis is the nature of evaluative terms and concepts. It investigates various phenomena that distinguish evaluative discourse from other types of language use. Broadly, the thesis argues that these differences are best explained by the hypothesis that evaluative discourse serves to communicate that the speaker is in a particular emotional or affective state of mind.

This thesis contributes to the ethical discussion on how to handle incidental findings in biomedical research using sequencing technologies from a theoretical and an empirical perspective.

Jennifer Viberg Johansson defends her PhD thesis. Opponent: Marion McAllister, Senior Lecturer, School of Medicine, Cardiff University

In aerospace applications, but also in manufacturing, mining, energy industry and natural hazards, high temperature, corrosion, erosion and radiation, challenge the performance and being of hardware.

Large-eddy simulation (LES) is a highly accurate turbulence modelling approach in which a wide range of spatial and temporal scales of the flow are resolved. However, LES becomes prohibitively computationally expensive when applied to wall-bounded flows at high Reynolds numbers, which are typical of many industrial applications.

Title: "New biomarkers for neuromuscular function and myasthenia gravis"

Title "Exposure to xenobiotic chemicals disrupts me-tabolism, rhythmicity and cell proliferation in Drosophila melanogaster".
The opponent is Prof. Jan Larsson from the Department of Molecular Biology, Umeå University.

This PhD thesis focuses on probabilistic methods of approximation of pluricomplex Green functions and is based on four papers.

Most species are constantly exposed to xenobiotic chemicals through multiple routes. Among all categories of xenobiotics, phthalates and bisphenols are two of the most widely used plasticizers and can be found in polyvinyl chloride (PVC) materials, medical devices and even drinking water.

In the last fifteen years, the Division of Electricity at Uppsala University has been developing a wave energy converter (WEC) concept. The concept is based on a point-absorbing buoy with a directly driven linear generator placed on the seabed.

In this thesis, I studied the evolution of reproductive isolation in the sister species Silene dioica (L.) Clairv. and S. latifolia Poiret.

The objective of this research was to facilitate the use of quantitative cardiac molecular imaging by developing and validating methods and applications.

Disputation: Olivier Donzel-Gargand, avd för fasta tillståndets elektronik, “The multiple faces of interfaces – Electron microscopy analysis of CuInSe2 thin-film solar cells”. 28 september kl 9.30, Polhemsalen. Opponent: Dr Daniel Abou-Ras, Department of Nanoscale Structures and Microscopic Analysis, Helmholz-Zentrum Berlin für Materialien und Energie, Berlin, Tyskland.

"Role of nuclear receptors in human adipose tissue metabolism"

This thesis explored the role of nuclear receptors, mainly, glucocorticoid and estrogen receptors (GR and ER, respectively) and peroxisome proliferator-activated receptor gamma (PPARγ), and their interplay in the regulation of metabolic function and dysfunction in human AT.

Using mainly electron microscopy characterization techniques, this thesis has explored the questions related to the interface control in thin-film photovoltaic solar cells based on CuInSe2 (CIS) absorber materials.

The purpose of the thesis is to identify, describe and interpret two series of terracotta objects from southern Ghana originally donated by Robert P. Wild to the British Museum in London between 1933 and 1936.

The purpose of this thesis is to present state of the art in radial basis function generated finite difference (RBF-FD) methods for pricing of financial derivatives. This work provides a detailed overview of RBF-FD properties and challenges that arise when the RBF-FD methods are used in financial applications.

Confirmation bias is a tendency to selectively search for and emphasize information that is consistent with a preferred hypothesis, whereas opposing information is ignored or downgraded. This thesis examines the role of confirmation bias in criminal cases, primarily focusing on the Swedish legal setting. It also examines possible debiasing techniques.

In this thesis we present some explorations within supergravity, a low energy limit of string theory, studying non-supersymmetric vacua, its stability, and the possibility of finding dS.

Disputation: Jun Luo, avd för tillämpad materialvetenskap, “Calcium phosphate based biomaterials for bone augmentation”. Opponent: Professor Marc Bohner, RMS Foundation, Bettlach, Schweiz.

Basic (apatite-based) calcium phosphate cements (CPCs), and acidic (brushite and monetite-based) CPCs are used as bone replacement materials because of their bioactivity, mouldability and ability to harden in place. However, their application is limited by their inherent brittleness and difficulties related to their handling. The current thesis aimed to provide solutions to these limitations.

The Amboseli ecosystem, home of Amboseli National Park, is renowned for its extraordinary biodiversity, and has long drawn the attention of conservationists and ecologists hoping to safeguard the healthy functioning of this Kenyan rangeland and the pastoral traditions that have brought this landscape into being.

The overall aim of this thesis was to expand the current knowledge regarding the advantages and limitations of computed tomography (CT) for patients with acute diverticulitis and evaluate outpatient treatment for uncomplicated diverticulitis.

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This thesis explores the interaction between people and technology by looking at the daily use of a business intelligence (BI) system in an automotive company’s sales process, where sellers use the system to analyze, report, and measure sales performance. The thesis is based on a single case study, and the data sources are in-depth interviews, observations, and archival data.

Environmental interactions, including both abiotic and biotic factors, are key drivers of life-history and population dynamics. Despite this, most population studies do not explicitly link variation in environmental factors and vital rates.

This thesis is devoted to the study of synthesis of causal filters for generating personal sound zones. Personal sound zones, personal audio or personal sound is the theory and practice of steering sound in such a way that it is amplified in one region and suppressed in another.

In university physics education, unequal student participation has always been an issue. An example is the fact that men constitute 70–80% of the student body in most countries. In recent years, physics education research has started to explore issues of participation, diversity, and identity, but more research and theoretical and methodological development is needed.

The overall aim of the current work was to expand knowledge of preeclampsia pathophysiology, with a main focus on the relationship between BNP and NT-proBNP, and early- and late-onset preeclampsia.

The external environment is complex: Antibiotics, metals and antimicrobials do not exist in isolation but in mixtures. Human activities such as animal husbandry, fertilization of agricultural fields and human medicine release high amounts these compounds into the environment.

The formation of successful physics students: Discourse and identity perspectives on university physics

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The aim of this thesis is to understand the influence of the deposition process and resulting film properties on Cu2ZnSnS4 (CZTS) thin film solar cells. Two main aspects are studied, namely formation of absorber precursors by sputtering, and alternative Cd-free buffer materials with improved band alignment.

The relationship between pet ownership and human health has been studied extensively; however, the effect of dog ownership on human health has had conflicting results. The overall aim of this research project was to investigate the impact of dog ownership, and the death of the dog, on human cardiovascular health and all-cause mortality.

Dissertation Le Fu, avd för tillämpad materialvetenskap, “Spark plasma sintered ZrO2-SiO2 glass ceramics and Si3N4 bioceramics”. Opponent: Professor Jérôme
Chevalier, Institut National des Sciences Appliquées de Lyon, Frankrike.

We study the low-energy sector of the strong interaction which is the least understood part of the Standard Model, the theory that describes the interactions of all known particles. The ideal particles for this study are the proton and the neutron, collectively called the nucleon.

This thesis focuses on elaboration and characterization of two types of bioceramics: one is ZrO2-SiO2 nanocrystalline glass ceramic (NCGC) for dental application. The goal is to develop new ZrO2-SiO2 NCGCs with a combination of high strength and high translucency; the other is biodegradable Si3N4 ceramics for spinal fusion.

Headquarters of multinational corporations are presented with a diverse range of stimuli that influences the issues that they pay attention to and ultimately get involved in. However, headquarters have to prioritize since their attention and resources are limited, and they cannot pay attention to all issues and get equally involved in all subsidiaries.

Amalia Nilsson defends her doctoral thesis: A Lighter Shade of Dark:
Exploring the Value Adding and Value Subtracting Effects of
Headquarters Attention and Involvement in Subsidiary Activities

Aim of the present thesis is to examine the outcomes of Superparamagnetic Iron Oxide (SPIO) nanoparticles, a new tracer based on magnetism for the detection of the sentinel nodes.

Disertation Oscar Janson, avd för tillämpad materialvetenskap, ”Bioactive coatings and antibacterial approaches for Titanium medical implants”. 12 oktober kl 9.15, Häggsalen. Opponent : Professor Pentti.
Tingvall, Göteborgs universitet.

The aim of this thesis was to characterize and manufacture coatings and surfaces with antibacterial properties and retained or enhanced bioactivity and biocompatibility. The aim was also to study the optimal composition and parameters of mixtures for debridement of bacterial biofilms on titanium surfaces.

Rational use of antibiotics–using antibiotics only when needed and in the right way–is a prioritized goal in policy aimed at preventing antimicrobial resistance. A vast body of research is devoted to understanding why unnecessary antibiotics are prescribed. However, this research tends to treat the definition of rational prescribing as an unproblematic fact, which is given by evidence.

Numbers are present everywhere, and when they are collected and recorded we refer to them as data. Machine learning is the science of learning mathematical models from data. Such models, once learned from data, can be used to draw conclusions, understand behavior, predict future evolution, and make decisions.

The Digital Cherenkov Viewing Device (DCVD) is an instrument used by authority safeguards inspectors to verify irradiated nuclear fuel assemblies in wet storage based on Cherenkov light emission. It is frequently used to verify that parts of an assembly have not been diverted, which is done by comparing the measured Cherenkov light intensity to a predicted one.

Why are flowers so diverse? Much of floral evolution is thought to be driven by pollinator-mediated selection. However, the connection between macroevolutionary patterns of floral diversity and microevolutionary processes remains poorly understood.

This thesis closely examines the Great Copper Mine in Falun in the first two decades of the eighteenth century. It uses a micro-historical approach to investigate the economic discourse of agrarian oeconomy, a complex idea tied to the early modern agrarian society.

Massively parallel sequencing (MPS) is revolutionizing genomics. In this work we use, refine, and develop new tools for the discipline.

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Species differentiation can be a consequence of evolutionary forces including natural selection and random genetic drift. Patterns of genomic differentiation vary across the tree of life. This variation seems to be dependent on, for example, differences in genomic architecture and molecular mechanisms.

The aim of this dissertation is to investigate how this notion of a threatening global crisis was visualized in Swedish public media during the 1970s.

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The diabetes disease panorama affects more than 400 million people world wide – a number projected to rise above 640 million in the next 20 years. Type 1 and type 2 diabetes are associated with adverse complications, resulting in severe morbidity and high healthcare costs exerting substantial strain on society.

This thesis examined the health systems effects of implementing the integrated Community Case Management (iCCM) intervention for paediatric febrile illnesses in a retail health market in South Western Uganda.

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On Tuesday, October 30th, Ronnie Mogensen will defend his licentiate thesis entitled "Solid electrolyte interphase stability in sodium-ion batteries" at 15.15 in 2005 at Ångström Laboratory.

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In this thesis, I have taken a population genetics approach; evaluating how the distribution of genetic variation in the human genome has been shaped through the actions of natural selection on functional genomic elements.

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Ubiquinones are a group of fat-soluble molecules present in many biological membranes. The most abundant version in humans, ubiquinone-10 (Q10), plays an important role in the mitochondrial respiration chain and also functions as a powerful antioxidant. Accumulating evidence suggests that Q10 also could have other functions in the membrane.

The present thesis examined whether disorganized attachment is a specific risk-factor for symptoms of Oppositional Defiant Disorder (ODD) or Attention-Deficit/Hyperactivity Disorder (ADHD), or a non-specific risk factor for both types of problems.

From framing private homes as museums, to sitting for life masks and appointing biographers, new forms of self-monumentalizing emerged in the early nineteenth century. In this study I investigate the emergence and configuration of such practices in Romantic Britain.

Thesis: ”Obesity, Sleep and Sleep-disordered Breathing”

Main supevisor: Eva Lindberg
Opponent: Ludger Grote, Sahlgrenska universitetssjukhuset, Göteborg

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The HER3 receptor plays a strong role in disease progression and resistance to therapies in several cancer types. Due to its endogenous expression and low overexpression in malignant tumours, it is a particularly challenging target. The primary aim of this thesis project was to develop, evaluate and characterize affibody molecules for theranostic applications in HER3-expressing malignant tumours.

Monika Rystedt Nyman will defend her doctoral thesis "Organizational Lessons Learned: Natural Hazards Affecting Critical Infrastructure."

This thesis presents an exploration of the resistance evolution in Escherichia coli towards the antibiotic ciprofloxacin. High level ciprofloxacin resistance is typically acquired by an accumulation of mutations and plasmid borne genes reducing drug target binding, increasing drug efflux, and modifying the drug.

In this thesis, the question of why a large number of small, modest, public baths (saunas) were built on the Swedish countryside during 1920–1949 has been analysed. The specific research question has been: How did the idea of the need for the baths, as well better personal hygiene among the Swedish population, develop?

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The objective of this thesis is to provide new understanding at a molecular level of important adsorbate species on the TiO2 surfaces.

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All their life, individuals have to make decisions that may strongly affect their fitness. To optimise their decisions, they can use personally acquired information but also information obtained from observing other individuals (“social information”).

The aim of this thesis was to explore women’s acute and longstanding experiences of taxane-induced pain, to evaluate the pain intensity and distribution using different assessment methods, and to study nurses´ perceptions of taxane-induced pain in people with breast cancer.

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To answer major evolutionary questions, we need a better understanding of the effects of mutations on specific functions and organism fitness. The aim of this thesis was to elucidate how new functions evolve and potential trade-offs with the original function.

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Public defence of doctor’s thesis (in Swedish)

The overall aim of this project was to investigate the clinical and ethical aspects of DNR decisions from the perspectives of nurses and physicians working in hematology and oncology care.

This is a thesis about expansions of consumer choice, their causal effects on political engagement, and the democratic implications that follow.

The overall aim was to describe and measure experiences among women and men after a miscarriage.

The overall aim of this thesis was to study post-operative complications in patients with rectal cancer.

The research summarized in this thesis focuses on synthesizing aldehyde and aldol compounds as substrates and products for the enzyme D-fructose-6-aldolase (FSA). Aldolases are important enzymes for the formation of carbon-carbon bonds in nature.

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Microgels as Carriers for Antimicrobial Peptides: Surface-bound microgels, and factors affecting peptide interactions

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Dynamic modelling of physical processes i magnetic systems: Dyke emplacement and flow-induced crystal rotations.

The main motivation for this thesis is to develop and improve numerical tools and methods that help further our comprehension of the volcanic plumbing system and its dynamics.

Even the most obvious actions require justification. The need for justification of peacebuilding involvements is always present. This thesis argues that justification is particularly needed when there is a prevalent power asymmetry between an external state and a host community.

On November 30, Ms. Ohlsson will be defending her dissertation "On the Ethics of External States in Peacebuilding – A Critical Study of Justification". Faculty opponent is Associate Prof Pamela Slotte (Helsinki University). Grading Committee: Assosiate Prof Elisabeth Gerle (Lund), Prof Helena Lindholm (Gothenburg), and Prof Ruben G. Apressyan (Moscow). Chair: Prof Elena Namli.

Titel: Towards new tools for clinical evaluation and visualization of tumor growth in patients with glioma

This book investigates the argument from queerness against moral realism, famously put forward by J. L. Mackie in Ethics: Inventing Right and Wrong (1977).

This thesis encompasses theoretical and computational studies of strongly correlated electron systems. Understanding how electrons in solids interact with each other is of great importance for future technology and other applications.

The aim of this thesis was to explore the associations between perinatal complications and perinatal maternal health, with emphasis on postpartum depressive symptoms (PPDS) and neuroticism taking into account potential confounding or mediating factors such as history of depression, antenatal depressive symptoms and delivery experience.

The aim of the thesis was to evaluate and hopefully define tumoral predictive markers for treatment with the common TKIs sunitinib and sorafenib.

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Opponent: Rolf Farnsteiner

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Seismicity and crustal strukture in Iceland: some studies of the Tjörnes Fracture Zone

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Lingshuang Kong defends her doctoral thesis: The Modern Journey to the West: Exploring Key Factors Influencing Reverse Knowledge Transfer in Emerging-market Multinationals

The dynamics of felsic magma emplacement in then upper crust.

This thesis had three major aims: 1) investigate regional permeability in human and rat intestines and evaluate two different rat models, 2) investigate the mechanisms behind absorption in nanosuspensions, and 3) investigate the effect of food on the absorption of drug molecules in solutions and suspensions, and also food’s effect on absorption modifying excipients (AMEs).

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This dissertation evaluates and compares when the assessment of mental abilities to refuse – or consent to – somatic medical intervention is required in England, Russia and Sweden, and what criteria must be applied to assess the ability to decide about somatic medical interventions in these legal orders.

Ocean energy is a growing field when it comes to renewable energy thanks to its high density of energy per unit area, and to the high predictability. Conversion of hydrokinetic energy, found in marine currents, is the utilization of the energy in free-flowing water for conversion to electric energy. This thesis presents experimental data from a test site with a marine current converter.

Johan Forslund, Department of electricity, “Studies of a vertical axis turbine for marine current energy conversion – Electrical system and turbine performance”. Opponent: Professor Cameron Johnstone, Mechanical and Aerospace Engineering, University of Strathclyde, Glasgow, Storbritannien.

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The overall aim of this qualitative study was to explore the function of religion and volunteer workers in religious organizations in contributing to the reconstruction and development of existential meaning and psychosocial well-being regarding the 2011 Great East Japan earthquake and tsunami.

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The overall aim with the studies has been to identify new biomarkers for cancer survival and potential therapeutic targets.

In this thesis, we evaluate the outcome of two faster implant protocols, in patients with compromised alveolar bone.

The overarching purpose of this thesis was to improve early recognition of both disability and ability in young autistic children. Three studies were conducted in a largely overlapping sample of 3-year-old high-risk-for-ASD siblings, either with or without ASD, and low-risk-for-ASD siblings.

Title: Anxious personality traits in pregnancy - associations with postpartum depression, delivery complications and Health care consumption

Anxious personality traits, including those encompassed by negative emotionality (neuroticism) and the tendency to worry about close relationships (attachment anxiety) during pregnancy were the focus of this thesis. The overall aim was to examine perinatal correlates of these characteris-tics in terms of psychiatric and obstetric health as well as antenatal care (ANC).

This thesis investigates the electronic structures on several perovskite oxide and halide materials with a focus on light harvesting applications.

In this thesis the links between housing tenure, income and selective, segregation generating, residential mobility are explored. The development of these links is analysed against the background of housing regime changes in Stockholm between 1990 and 2014.

This dissertation is a study of modern Indian philosophy.

Acute limb ischaemia (ALI) is a frequent emergency associated with high rates of amputation and death. Traditionally, patients with ALI were treated with open surgical removal of the occlusion or bypass surgery. During the past few decades, new endovascular techniques developed.

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In vitro evaluation of formulations used in the treatment of hepatocellular carcinoma

Neuroblastoma (NB) is one of the most common childhood cancers. Patients with low stage tumor have high survival rate, while those with advanced stage and/or unfavorable molecular biology have poor prognosis.

The purpose of the study was to explore the role of religion in the development of a meaning system among Swedish adolescents by examining the interactions of their: sense of coherence (SOC), identity process (U-MICS), moral development (SRM-SF), and views on existential and religious questions.

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In this thesis, I present three studies where we have characterized different enzyme families by structural and biochemical methods. The studies demonstrate the occurrence of enzyme promiscuity and its potential role in evolution and organismal adaptation.

This thesis explores the diverse consequences of transnational labour migration on individual migrants and their household members within out-migration communities in the agricultural valleys of Cochabamba, Bolivia.

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Disputation: Petter Eklund, Division of Electricity, ”Design of rare earth free permanent magnet generators”. Opponent: Docent Oskar Wallmark, KTH.

Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.

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Improved Molecular Understanding of Lipid-Based Formulations: for Enabling Oral Delivery of Poorly Water-Soluble Drugs

The aim of this thesis was to develop new models, that by acknowledging the complexity of the data captures more information, and novel methodologies for model evaluation, as well as applying models to improve study designs, with practical illustrations in the therapeutic area of diabetes. Two new models were developed.

This dissertation examines uses of history and expressions of cultural memory in Norwegian black metal.

When a program is compiled and run on a modern architecture, different optimizations may be applied to gain in efficiency. In particular, the access operations (e.g., read and write) to the shared memory may be performed in an out-of-order manner, i.e., in a different order than the order in which the operations have been issued by the program.

Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. Except its conventional enzymatic function, non-enzyme function and its function in the nucleus have been demonstrated recently.

References are a programming language construct that lets a programmer access a datum invariant of its location.

The current thesis describes new data on the adhesion-linked molecular mechanisms regulating cytokinesis and centrosomes.

The overall aim of this thesis is to aid in drug discovery against leishmaniasis – primarily using bio- and chemoinformtic approaches.

Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs).

This thesis theoretically studies the dynamics of molecular magnets under electrical control.

This thesis addresses the physics of collisionless shocks using spacecraft observations of the Earth's bow shock, particularly understanding the ion dynamics and shock structure for different shock conditions.

Disputation: Francisco Francisco, Division of Electricity, ”Adapting sonar systems for monitoring ocean technologies”. Opponent: Professor William Megill, Rhine Waal University of Applied Sciences, Kleve, Germany.

This thesis focus on a sustainable implementation of wave, tidal and offshore wind power, wherefore there is a need to investigate more about the prerequisites and consequences ocean energy can have on the marine environment. For that, reliable, cost effective and continuous environmental monitoring framework is necessary in order to support and safeguard ocean energy operations.

The primary aim of this dissertation is to gain a greater understanding of the particular vulnerabilities attached to wo/men publicly performing atheist selves on YouTube.

The overall aim of this thesis was to evaluate the clinical management of AUD with regard to the no-antibiotic policy and its long-term effect, treatment on an outpatient basis and the potential health-care cost savings.

In this thesis, a new type of material, i.e. Cladophora cellulose, is used to manufacture separators for LIBs and lithium-metal batteries (LMBs). The separators, made with Cladophora cellulose fibers via a straightforward paper making method, possess several advantages compared to conventional polyolefin separators.

Flood Prediction in data-scarce basins - Maximising the value of limited hydro-meteorological data.

This thesis aimed to investigate the anti-bacterial properties and antibiotic-induced inflammatory responses of ß-lactam antibiotic compared with effects of the addition of an aminoglycoside in clinically relevant E. coli porcine intensive care sepsis/septic shock models. We also studied the host's antibacterial capacities in primary and secondary sepsis.

In recent decades, the theory of deliberative democracy has encountered multiple challenges. In this thesis, I explore the prospects of a particular type of deliberative democratic institution – deliberative mini-publics – in three essays.

The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood.

In this thesis we investigated associations between a high birth weight and risk of adult disease, e.g. obesity, cardiovascular disease, type 2 diabetes and gestational diabetes.

Bone is a tissue that heals by itself, unless the defect is too large (critical size). Today, novel regenerative medicine approaches have emerged as an alternative to treat such defects. This thesis explores alternative therapeutic strategies for bone tissue engineering which are biocompatible and clinically translatable.

Exploring links between melatonin, inflammation and depression

The focus of this thesis was to study the relationship between inflammation, melatonin and symptoms of depression.

Application performance on computer processors depends on a number of complex architectural and microarchitectural design decisions. Consequently, computer architects rely on performance modeling to improve future processors without building prototypes. This thesis focuses on performance modeling and proposes methods that quantify the impact of the memory system on application performance.

This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior.

Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure

In this PhD thesis, ab initio density functional theory along with molecular dynamics and global optimization methods are used to unveil and understand the structures and properties of energy relevant materials.

Title: "Neuromolecular and behavioural profile of teleosts - effects of boldness, agonistic behaviour and reproductive status".

This thesis investigates if boldness is reflected in the function of brain histaminergic system in zebrafish (Danio rerio). Moreover, behavioural differences in AB line, spiegeldanio (spd) line and wild caught strain of zebrafish have also been explored apart from the winner-loser effect in AB and spd fish.

This thesis contributes to the field of carbonyl olefinations and presents the development of a new synthetic protocol for a one-pot reductive coupling of two aldehydes to alkenes based on organophosphorus chemistry.

The overall aim of this thesis was to analyse underlying factors that facilitate the dissemination of multiresistant pathogenic bacteria in hospital settings.

The recent field of analysis on fractals has been studied under a probabilistic and analytic point of view. In this present work, we will focus on the analytic part developed by Kigami. The fractals we will be studying are finitely ramified self-similar sets, with emphasis on the post-critically finite ones.

Ancient artefacts appeared frequently in late-nineteenth and early-twentieth-century British fiction. Prehistoric stone circles, enigmatic potsherds, Egyptian mummies, and other such antiquities featured in everything from fin de siècle adventure narratives to the major works of High Modernism.

This thesis explores prostasomes and their ability to be used as a new diagnostic tool for prostate cancer. Alongside diagnosis, this thesis also suggests prostasomes as a tool for prognosis and therapeutic treatment in patients with prostate cancer.

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Photochemical energy conversion into solar fuel involves steps of light absorption, charge separation and catalysis. Nature has taught us that the effective accumulation of redox equivalents and charge separation are the key steps in sunlight conversion. The focus of this thesis is to unveil photophysical and photochemical processes that lead to accumulative charge separation.

This book examines some central arguments in the debate about the value of death.

This thesis adds to previous work on significant but less pronounced key features for successful organization of primary diabetes care, and indicates that the complexity of diabetes disease makes it difficult to identify success factors applicable to all people living with T2DM.

In this thesis I aim to comprehensively characterize and quantify genetic variation in a natural system, the songbird genus Corvus.

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In this thesis, we used proteomics to identify the major excretory-secretory products (ESPs) released by Giardia trophozoites of the WB and GS isolates during interaction with intestinal epithelial cells (IECs) in vitro (Paper I).

Public defence of doctoral thesis

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The overall aim was to gather data about pre- and postsurgical factors of importance and long-term outcomes to improve standards of care. Another aim was to explore the expression of somatostatin receptor (SSTR) subtypes and mTOR pathway markers.

The field of two-dimensional (2D) layered materials provides a new platform for studying diverse physical phenomena that are scientifically interesting and relevant for technological applications. Novel applications in electronics and energy storage harness the unique electronic, optical, and mechanical properties of 2D materials for design of crucial components.

The overall aim of the thesis is to contribute with new and deepened knowledge about the teaching and learning of craft when the crafting activity is considered as environmental and sustainability education (ESE).

This thesis aims to develop an epistemology of rhetoric in light of the apparent contemporary post-truth condition of society. Epistemology is hereby understood as concerned with principles for knowledge production within the academic discipline of rhetoric, as well as with an understanding of knowledge production in the public realm.

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Titel: "Metabolic health and cognitive function: the roles of lifestyle and shift work"

The aim of this thesis was to investigate associations of diet, sleep, and shift work with metabolic health or cognitive performance in two Swedish cohorts.

Public defence within the field of Molecular Biology

This thesis clarifies intriguing enzymology of the ribosome, the multiRNA/multiprotein complex that catalyzes protein synthesis (translation).

Altogether, this thesis contributes to our understanding of ErbB3 cellular functions and modes of regulation, unveiling new roles of this RTK in vesicular trafficking and exosome release, and proposing Ack1 as a novel modulator of its function.

By exploring representations of place, this thesis treats practices of spatial stigmatisation in the context of segregated Swedish cities. In three papers, different aspects of stigmatisation and place-making are discussed and analysed, where the overarching ambition is to identify and critically deconstruct the ideology behind stigma as well as suggest ways of making representation positive.

This thesis work is based on the development of novel organopnictogen compounds and the exploration of their potential applications in organic electronics. In particular, incorporation of phosphorus and arsenic into π-conjugated systems is known to modify the optoelectronic properties.

Researchers use knowledge elicitation methods to document expert knowledge for the primary purpose of understanding cognitive processes and with this understanding, technical solutions to resolve human factors issues can be produced. This dissertation offers a novel perspective on knowledge elicitation as an abstraction process.

Risk-taking is an important topic in Africa, as access to financial institutions and social security is scarce. Data on risk attitudes in Africa is limited and the available data collected might not be reliable.

Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease.

Improved means to assess the clinical potential of drug candidates can critically influence development of new therapeutic entities, a central aim in medical life science. Drug discovery and development relies on construction and selection of small organic compounds or biological agents that bind targets of interest. This thesis includes new methodology to investigate target engagement.

In this thesis, we mainly focus on developing approaches for the inversion of scattering and absorption coefficients from optically measured transmittance and reflectance spectra.

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Disputation Per Fors, avd Industriell teknik, "Problemazing Sustainable ICT". Opponent: Professor Saara Taalas, Linnéuniversitetet.

Disputation Sabina Huc, division of applied mechanics, "Moisture induced strains and stresses in Wood". Opponent Professor Sigurdur Ormarsson, Linnéuniversitetet.

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This book studies how domestic courts and commercial arbitration institutions impact the scope of arbitral tribunal jurisdiction in investment treaty disputes.

This research explores how entrepreneurship interacts with feministic political commitments and praxis. It shows that this interaction is intimately shaped by its spatial setting, in this case Möllevången in the city of Malmö, Sweden.

Platelet-derived growth factor receptor (PDGFR) signaling is essential for proliferation, migration and survival of cells of mesenchymal origin; however, its deregulation has been associated with various diseases, including cancer. The aim of this thesis was to clarify the molecular mechanisms of PDGFR signaling regulation.

This thesis aims to obtain an understanding of immigrant women’s access to healthcare services in Sweden in relation to sexual and reproductive health and rights (SRHR). Data were obtained from three different quantitative cross-sectional studies using self-administrated questionnaires and one qualitative study based on in-depth interviews.

This thesis focuses on the automation of seismic data analysis, in particular, event detection, quality assessment of detected events, and preparation of an earthquake catalogue for seismic tomography.

A multidisciplinary approach was adopted in this study of quick clays in an area of southwest Sweden that is prone to landslides. It was mainly based on geophysical methods, but was complemented and validated with geotechnical, geological, and hydrological data.

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This thesis concentrates on two questions: What beliefs do ministers have of appropriate steering in the Swedish core executive Regeringskansliet (RK)? Do they believe that RK is a politically steered organization as it is usually described, or as a throughout political organization, as some political scientists have recently depicted it?

Autosomal recessive congenital ichthyosis (ARCI) is a rare monogenetic disorder characterized by a defective skin barrier, hyperkeratosis, and dry, scaly skin. It affects keratinocyte differentiation and is caused by mutations in any of at least 12 genes believed to control the formation of ω-O-acylceramide and the corneocyte lipid envelope

In this work, we examined the feasibility of having an allogeneic source of vaccine-DCs (alloDCs), not for direct antigen-presentation to T cells but as an immune primer aiming to activate bystander DCs.

The aim of this study is to explain why human geography in Sweden became a planning science during the postwar period. Human geography had developed a sophisticated use of abstract models. The proliferation of models within in the social sciences was an international phenomenon during the postwar period.

The overall aim of this thesis was to develop and evaluate new virtual planning tools for CMF-surgery and to investigate their usefulness.

Children born small for gestational age (SGA) run increased risk of perinatal morbidity and mortality, but also of long-term health impairment. Risks on long term may vary depending on postnatal growth patterns. The overall aim of the thesis was to gain further knowledge about long-term consequences of being born SGA, as well as the impact of perinatal exposures on postnatal growth patterns.

The overall aim of this thesis was to examine the impact of nutrition, exercise and body composition on function, wellbeing and mortality in community-dwelling older adults.

Disputation

Disputation: Man Song, div Solid State Electronics, “Graphene Based Inks for Printed Electronics”. Opponent: PhD Anwar Ahniyaz, RISE.

Yuanyuan Han, Department of Applied Material Science, ”Biosensing platforms using graphene based bioreactive nanostructures with various dimensions”,Opponent: Dr. Rabah Boukherroub, Université de Lille, France.

The overall aim of this thesis was to investigate factors with relevance to adherence, to estimate treatment effects with the time-based Delay of Event (DoE) measure in anticoagulant preventive treatments, and to explore how lay people responded to the DoE measure, as compared with established measures, regarding treatment decisions and effect interpretation.

This thesis investigates the complex relationship between residential segregation and social integration. The dominant discourse in Sweden and Europe sees residential segregation as hindering socioeconomic and cultural integration, creating parallel societies and even threatening the social cohesion of European societies.

This thesis aimed to investigate the associations between asthma control, asthma-related comorbidity, and sleep. Insomnia symptoms with asthma are common, and have commonly been explained by poor asthma control and asthma symptoms during the night, which affect most asthmatics to some degree.

The aim of this thesis was to develop pharmacometric models to optimise the development and use of current and future drugs for treating tuberculosis.

The present thesis took a developmental and individual differences approach to understanding action perception and processing in infancy. The overarching aim was to understand the development of action perception and how individual differences contribute to the perception and processing of actions.

How to generate and use electricity in a more efficient way is a major challenge for humankind. In this context, permanent magnets play an important role within a very broad range of electric power applications. The strongest magnets used today are mainly based on alloys that contain rare-earth metals, which are neither economical nor sustainable.

The aim of this thesis was to study the working life of first-line managers and their subordinates in elderly care from an empowerment perspective.

Computerized analysis of handwritten documents is an active research area in image analysis and computer vision. The goal is to create tools that can be available for use at university libraries and for researchers in the humanities. Working with large collections of handwritten documents is very time consuming and many old books and letters remain unread for centuries.

The London Measure of Unplanned Pregnancy (LMUP) and the Swedish Pregnancy Planning Scale (SPPS) are two measurements of pregnancy planning. Adverse childhood experiences (ACEs) and childhood abuse are stressful events that have been suggested to have both short- and long-term effects.

Markus Eriksson, div. Signals and systems, "Change Point Detection with Applications to
Wireless Sensor Networks". Opponent: Professor Idris Eckley, Department of
Mathematics and Statistics, Lancaster University, UK.

In this thesis work we develop a new algorithm for detecting joint changes in statistical behavior of multiple, simultaneously recorded, signals. Such signal analysis is commonly known as multivariate change point (CP) detection (CPD) and is of interest in many scientific and engineering applications.

Public defence

In this thesis, the S. salmonicida genome was sequenced and compared to the genome of its diplomonad relative, the mammalian pathogen G. intestinalis (Paper I). Our analyses revealed large genomic differences between the two parasites that collectively suggests that S. salmonicida is more capable of adapting to different environments.

Disputation

The increase in the number of wind turbines (WTs) in populated areas in cold climates increases the number of people potentially being affected by WT sound. Outdoor sound propagation is strongly dependent on meteorological conditions, however, limitations in the knowledge exist regarding the implications of meteorological conditions in cold climates.

The overall aim of the work presented in here was to investigate PFBC related calcifications and analyze the effects of impaired PDGF-B/PDGFR-b signaling on the formation of brain calcifications in different mouse models.

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This thesis evaluates passive denitrifying woodchip bioreactors (DWBs) for the removal of nitrate (NO3-) in neutral pH mine drainage, where water is passed through a carbon-rich porous matrix (e.g. woodchips) for the reduction of NO3- to nitrogen gas.

In this thesis, a set of different technologies that can be used to analyze digital environments from a security perspective are presented.

This study gives an in-depth insight into ways that ordinary Christians in a multireligious context think about religious plurality. It examines how Indian Protestants reflect upon other religions and upon the situation of religious diversity.

Disputation

This thesis focuses on weight-loss, effect on comorbidities, quality of life and complications after DS and RYGB, respectively, with comparisons between the two procedures in patients with super obesity.

Maria Angeliki Chatzigiannakou, "Offshore deployments of marine energy converters”, Opponent: Tony Lewis, University College Cork, Irland.

The focus of this thesis is the wave and marine current energy researched at the division of Electricity at Uppsala University (UU).

Disputation

In 2009, a pharmacy policy reform was introduced in Sweden whereby the state owned community pharmacy monopoly was abolished. This thesis studied the diversity rationale behind the pharmacy reform and compared it to the primary care reform. The results show that, in both cases, policy makers definitions of diversity were vague and unclear, which appear to have complicatedand new owners appeared.

This dissertation studies the efficacy and effects of coercive policies in the context of the Israel-Palestine conflict. The four composite essays investigate the impact of Israel’s practice of house demolition and construction of a separation barrier on Palestinians’ conflict preferences and use of violence, as well as the broader consequences of these policies for Palestinian communities.

The aim of this thesis was to evaluate and explore the provision of childbirth care, focusing on obstetric fistula as one of its complications, in a rural Mozambican setting of high facility delivery rate.

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Zhen Qiu, "Transition Metal-Based Electrocatalysts for Alkaline Water Splitting and CO2 Reduction".Opponent: Professor Kevin Sivula, École polytechnique fédérale de Lausanne,

Transition metal-based electrocatalysts for alkaline water splitting and CO2 reduction

Mohd Nasir Ayob, ”Adaption of wave power plants to regions with high tides”. Opponent: Professor Ian Masters, UK.

Disputation

The aims of this thesis were to investigate effects of timing of umbilical cord clamping on newborn health, and on infant outcomes up to 12 months of age in a high-risk population and to explore the context of implementing changed umbilical cord clamping practices in Nepal.

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This thesis presents a comprehensive study on design, fabrication, and noise reduction of SiNWFET-based sensors on silicon-on-oxide (SOI) substrate.

Disputation

Xi Chen, Div. Solid state electronics,”Silicon Nanowire Field-Effect Devices as Low Noise Sensors”. Opponent: Professor Fengnian Xia, Yale University, USA.

Public defence

Molecular-mechanical (MM) force fields are mathematical functions that map the geometry of a molecule to its associated energy. MM force fields have been extensively used for an atomistic view into the dynamic and thermodynamics of large molecular systems in their condensed phase.

Disputation

The aim of this thesis was to investigate the role of genetic background on susceptibility to develop acute decompensated heart failure.

In this thesis, we have envisaged systematic investigation to predict the water splitting mechanism on ultra-thin two-dimensional (2D) materials using cutting edge computation.

I evaluated eight plant species for their toxicity and repellency against nymphs of Ixodes ricinus (Acari: Ixodidae), the most important life cycle stage of tick-borne infection of humans.

Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A

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Disputation: Maria Vall, division of nanotechnology and functional materials, ”Development of nanoporous inorganic carbonates for pharmaceutical and environmental applications”. Opponent: Prof. Jessica Rosenholm, Åbo Akademi.

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Opponent: Petter Andreas Bergh from NTNU (Trondheim)

The overall aim of this thesis was to investigate associations between proteomic and metabolomic biomarkers, and the development of heart failure and ischemic stroke. Specific objectives were to examine potential causal pathways, and the added value in risk prediction of the identified risk markers.

Public defence

This thesis addresses two questions regarding the accuracy of protein synthesis. How do bacterial and eukaryotic release factors ensure accurate termination? How do mRNA modifications affect the accuracy of bacterial protein synthesis?

The overall aim was to describe characteristics and health issues that insti-gate help seeking behavior among frequent attenders and to piece together a treatment program addressing heterogeneous health problems with the pur-pose to reduce psychological distress, enhance quality of life and reduce visiting rates at general practitioners.

Aim: To investigate associations between different aspects of SDB and cardiovascular disease in women.

Pharmacometric models in the development of biological medicinal products

Public defence

This thesis contains studies on degradation processes in Li-ion batteries utilizing the LiNixMnyCozO2 (NMC) cathode material, and suggests strategies for the improvement of battery life time.

In this thesis work, pharmacometric models and methods were developed and applied to aid BMP development and clinical use.

Long-term consequences after severe burn injury

This thesis investigated the role of burn-specific and individual-related factors for long-term outcome after burn with emphasis on pruritus, pain, personality and perceived health.

This thesis summarizes my work on the investigation of the photoinduced electron transfer in lanthanide complexes. Chapter 1 is a brief introduction. Chapter 2 describes a structure-activity relationship in a focused library of lanthanide complexes. PeT was observed with most antennae and in a larger of lanthanides than previously assumed.

Mudassir Imran Mustafa U-CARE co-worker and joint PhD student at the Department of Informatics and Media, and Department of Women's and Children's health Uppsala University, is defending his dissertation "Sustaining the Usefulness of eHealth Research Software - Lessons Learned in Action Design Research" on June 10 13:00 at Ekonomikum Hörsal 2, Kyrkogårdsgatan 10, 751 20 Uppsala.

Mudassir Imran Mustafa will defend his doctoral thesis “Sustaining the Usefulness of eHealth Research Software: Lessons Learned in Action Design Research”.

In this thesis, I focus on disentangling the relative roles of these evolutionary mechanisms and genetic factors in determining rates and patterns of evolution at the molecular level, by studying variation in the DNA sequence of multiple avian species, and in particular the collared flycatcher (Ficedula albicollis).

This thesis examines archaeological approaches to burials and changing mortuary practices during the Late Iron Age (c. 500-1100 AD) in central Eastern Sweden. Understanding the change in mortuary practices is fundamental to the study of the Late Iron Age.

Disputation: Jie Zhao, "Solution-Processable Conductive Graphene-Based for Flexible Electronics". Opponent: Professor Matti Mäntysalo, Tampere University of Technology.

This thesis aimed to investigate seasonal aspects of peripartum depressive symptoms (PPDS) and biological markers during the peripartum period.

Disputation

The aim of this thesis was to investigate biological and clinical aspects of G3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs).

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Peter Ek defends his doctoral thesis: Managing Digital Open Innovation with User Communities: A Study of Community Sensing and Product Openness Capabilities in the Video Game Industry

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Public defence

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The focus of this thesis is on the development of molecular tweezers as host-guest systems for stereochemical characterization of small organic molecules.

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If only I could sleep – maybe, I could remember

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The aim of this dissertation is to shed light on the institutional categorization process involving persons with mental ill-health in two interrelated areas of welfare settings: primary healthcare and sickness insurance.

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In this thesis, I explore genetic variation and the contemporary evolutionary processes affecting genes involved in the adaptive immune defense (Major Histocompatibility Complex; MHC) and the innate immune defense (AMP; Antimicrobial Peptides) over a large geographical gradient in anuran species.

This thesis provides an analysis of the evolution of discrete traits and their effect on the birth and survival of species using the theory of supercritical, continuous time Markov branching processes.