Kalendarium

The objective of this thesis is to provide new understanding at a molecular level of important adsorbate species on the TiO2 surfaces.

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All their life, individuals have to make decisions that may strongly affect their fitness. To optimise their decisions, they can use personally acquired information but also information obtained from observing other individuals (“social information”).

The aim of this thesis was to explore women’s acute and longstanding experiences of taxane-induced pain, to evaluate the pain intensity and distribution using different assessment methods, and to study nurses´ perceptions of taxane-induced pain in people with breast cancer.

To answer major evolutionary questions, we need a better understanding of the effects of mutations on specific functions and organism fitness. The aim of this thesis was to elucidate how new functions evolve and potential trade-offs with the original function.

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The overall aim of this project was to investigate the clinical and ethical aspects of DNR decisions from the perspectives of nurses and physicians working in hematology and oncology care.

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This is a thesis about expansions of consumer choice, their causal effects on political engagement, and the democratic implications that follow.

The overall aim was to describe and measure experiences among women and men after a miscarriage.

The overall aim of this thesis was to study post-operative complications in patients with rectal cancer.

Mikrogeler som bärare av antimikrobiella peptider:Om ytbundna mikrogeleroch faktorer som påverkar peptidinteractioner

The research summarized in this thesis focuses on synthesizing aldehyde and aldol compounds as substrates and products for the enzyme D-fructose-6-aldolase (FSA). Aldolases are important enzymes for the formation of carbon-carbon bonds in nature.

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Dynamic modelling of physical processes i magnetic systems: Dyke emplacement and flow-induced crystal rotations.

The main motivation for this thesis is to develop and improve numerical tools and methods that help further our comprehension of the volcanic plumbing system and its dynamics.

Even the most obvious actions require justification. The need for justification of peacebuilding involvements is always present. This thesis argues that justification is particularly needed when there is a prevalent power asymmetry between an external state and a host community.

On November 30, Ms. Ohlsson will be defending her dissertation "On the Ethics of External States in Peacebuilding – A Critical Study of Justification". Faculty opponent is Associate Prof Pamela Slotte (Helsinki University). Grading Committee: Assosiate Prof Elisabeth Gerle (Lund), Prof Helena Lindholm (Gothenburg), and Prof Ruben G. Apressyan (Moscow). Chair: Prof Elena Namli.

Titel: Towards new Tools for Clinical evaluation and visualization of tumor growth in patients with glioma.

This book investigates the argument from queerness against moral realism, famously put forward by J. L. Mackie in Ethics: Inventing Right and Wrong (1977).

This thesis encompasses theoretical and computational studies of strongly correlated electron systems. Understanding how electrons in solids interact with each other is of great importance for future technology and other applications.

The aim of this thesis was to explore the associations between perinatal complications and perinatal maternal health, with emphasis on postpartum depressive symptoms (PPDS) and neuroticism taking into account potential confounding or mediating factors such as history of depression, antenatal depressive symptoms and delivery experience.

The aim of the thesis was to evaluate and hopefully define tumoral predictive markers for treatment with the common TKIs sunitinib and sorafenib.

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Opponent: Rolf Farnsteiner

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Seismicity and crustal strukture in Iceland: some studies of the Tjörnes Fracture Zone

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Lingshuang Kong försvarar sin doktorsavhandling i företagsekonomi: The Modern Journey to the West: Exploring Key Factors Influencing Reverse Knowledge Transfer in Emerging-market Multinationals

The dynamics of felsic magma emplacement in then upper crust.

This thesis had three major aims: 1) investigate regional permeability in human and rat intestines and evaluate two different rat models, 2) investigate the mechanisms behind absorption in nanosuspensions, and 3) investigate the effect of food on the absorption of drug molecules in solutions and suspensions, and also food’s effect on absorption modifying excipients (AMEs).

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This dissertation evaluates and compares when the assessment of mental abilities to refuse – or consent to – somatic medical intervention is required in England, Russia and Sweden, and what criteria must be applied to assess the ability to decide about somatic medical interventions in these legal orders.

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Ocean energy is a growing field when it comes to renewable energy thanks to its high density of energy per unit area, and to the high predictability. Conversion of hydrokinetic energy, found in marine currents, is the utilization of the energy in free-flowing water for conversion to electric energy. This thesis presents experimental data from a test site with a marine current converter.

The overall aim of this qualitative study was to explore the function of religion and volunteer workers in religious organizations in contributing to the reconstruction and development of existential meaning and psychosocial well-being regarding the 2011 Great East Japan earthquake and tsunami.

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The overall aim with the studies has been to identify new biomarkers for cancer survival and potential therapeutic targets.

In this thesis, we evaluate the outcome of two faster implant protocols, in patients with compromised alveolar bone.

The overarching purpose of this thesis was to improve early recognition of both disability and ability in young autistic children. Three studies were conducted in a largely overlapping sample of 3-year-old high-risk-for-ASD siblings, either with or without ASD, and low-risk-for-ASD siblings.

Title: Anxious personality traits in pregnancy - associations with postpartum depression, delivery complications and Health care consumption

Anxious personality traits, including those encompassed by negative emotionality (neuroticism) and the tendency to worry about close relationships (attachment anxiety) during pregnancy were the focus of this thesis. The overall aim was to examine perinatal correlates of these characteris-tics in terms of psychiatric and obstetric health as well as antenatal care (ANC).

This thesis investigates the electronic structures on several perovskite oxide and halide materials with a focus on light harvesting applications.

In this thesis the links between housing tenure, income and selective, segregation generating, residential mobility are explored. The development of these links is analysed against the background of housing regime changes in Stockholm between 1990 and 2014.

This dissertation is a study of modern Indian philosophy.

Acute limb ischaemia (ALI) is a frequent emergency associated with high rates of amputation and death. Traditionally, patients with ALI were treated with open surgical removal of the occlusion or bypass surgery. During the past few decades, new endovascular techniques developed.

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In vitro utvärdering av formuleringar använda i behandlingen av Hepatocellulär carcinoma

Neuroblastoma (NB) is one of the most common childhood cancers. Patients with low stage tumor have high survival rate, while those with advanced stage and/or unfavorable molecular biology have poor prognosis.

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In this thesis, I present three studies where we have characterized different enzyme families by structural and biochemical methods. The studies demonstrate the occurrence of enzyme promiscuity and its potential role in evolution and organismal adaptation.

This thesis explores the diverse consequences of transnational labour migration on individual migrants and their household members within out-migration communities in the agricultural valleys of Cochabamba, Bolivia.

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Disputation: Petter Eklund, avd för elektricitetslära, ”Design of rare earth free permanent magnet generators”. Opponent: Docent Oskar Wallmark, KTH.

Improved Molecular Understanding of Lipid-Based Formulations: for Enabling Oral Delivery of Poorly Water-Soluble Drugs

Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.

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The aim of this thesis was to develop new models, that by acknowledging the complexity of the data captures more information, and novel methodologies for model evaluation, as well as applying models to improve study designs, with practical illustrations in the therapeutic area of diabetes. Two new models were developed.

This dissertation examines uses of history and expressions of cultural memory in Norwegian black metal.

When a program is compiled and run on a modern architecture, different optimizations may be applied to gain in efficiency. In particular, the access operations (e.g., read and write) to the shared memory may be performed in an out-of-order manner, i.e., in a different order than the order in which the operations have been issued by the program.

Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. Except its conventional enzymatic function, non-enzyme function and its function in the nucleus have been demonstrated recently.

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The current thesis describes new data on the adhesion-linked molecular mechanisms regulating cytokinesis and centrosomes.

Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs).

The overall aim of this thesis is to aid in drug discovery against leishmaniasis – primarily using bio- and chemoinformtic approaches.

This thesis theoretically studies the dynamics of molecular magnets under electrical control.

This thesis addresses the physics of collisionless shocks using spacecraft observations of the Earth's bow shock, particularly understanding the ion dynamics and shock structure for different shock conditions.

Disputation: Francisco Francisco, avd för elektricitetslära, ”Adapting sonar systems for monitoring ocean technologies”. Opponent: Professor William Megill, Rhine Waal University of Applied Sciences, Kleve, Tyskland.

This thesis focus on a sustainable implementation of wave, tidal and offshore wind power, wherefore there is a need to investigate more about the prerequisites and consequences ocean energy can have on the marine environment. For that, reliable, cost effective and continuous environmental monitoring framework is necessary in order to support and safeguard ocean energy operations.

The primary aim of this dissertation is to gain a greater understanding of the particular vulnerabilities attached to wo/men publicly performing atheist selves on YouTube.

The overall aim of this thesis was to evaluate the clinical management of AUD with regard to the no-antibiotic policy and its long-term effect, treatment on an outpatient basis and the potential health-care cost savings.

In this thesis, a new type of material, i.e. Cladophora cellulose, is used to manufacture separators for LIBs and lithium-metal batteries (LMBs). The separators, made with Cladophora cellulose fibers via a straightforward paper making method, possess several advantages compared to conventional polyolefin separators.

Flood Prediction in data-scarce basins - Maximising the value of limited hydro-meteorological data.

This thesis aimed to investigate the anti-bacterial properties and antibiotic-induced inflammatory responses of ß-lactam antibiotic compared with effects of the addition of an aminoglycoside in clinically relevant E. coli porcine intensive care sepsis/septic shock models. We also studied the host's antibacterial capacities in primary and secondary sepsis.

In recent decades, the theory of deliberative democracy has encountered multiple challenges. In this thesis, I explore the prospects of a particular type of deliberative democratic institution – deliberative mini-publics – in three essays.

The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood.

In this thesis we investigated associations between a high birth weight and risk of adult disease, e.g. obesity, cardiovascular disease, type 2 diabetes and gestational diabetes.

Bone is a tissue that heals by itself, unless the defect is too large (critical size). Today, novel regenerative medicine approaches have emerged as an alternative to treat such defects. This thesis explores alternative therapeutic strategies for bone tissue engineering which are biocompatible and clinically translatable.

Exploring links between melatonin, inflammation and depression

The focus of this thesis was to study the relationship between inflammation, melatonin and symptoms of depression.

Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure

Application performance on computer processors depends on a number of complex architectural and microarchitectural design decisions. Consequently, computer architects rely on performance modeling to improve future processors without building prototypes. This thesis focuses on performance modeling and proposes methods that quantify the impact of the memory system on application performance.

This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior.

In this PhD thesis, ab initio density functional theory along with molecular dynamics and global optimization methods are used to unveil and understand the structures and properties of energy relevant materials.

Title: "Neuromolecular and behavioural profile of teleosts - effects of boldness, agonistic behaviour and reproductive status".

This thesis investigates if boldness is reflected in the function of brain histaminergic system in zebrafish (Danio rerio). Moreover, behavioural differences in AB line, spiegeldanio (spd) line and wild caught strain of zebrafish have also been explored apart from the winner-loser effect in AB and spd fish.

This thesis contributes to the field of carbonyl olefinations and presents the development of a new synthetic protocol for a one-pot reductive coupling of two aldehydes to alkenes based on organophosphorus chemistry.

The overall aim of this thesis was to analyse underlying factors that facilitate the dissemination of multiresistant pathogenic bacteria in hospital settings.

The recent field of analysis on fractals has been studied under a probabilistic and analytic point of view. In this present work, we will focus on the analytic part developed by Kigami. The fractals we will be studying are finitely ramified self-similar sets, with emphasis on the post-critically finite ones.

Ancient artefacts appeared frequently in late-nineteenth and early-twentieth-century British fiction. Prehistoric stone circles, enigmatic potsherds, Egyptian mummies, and other such antiquities featured in everything from fin de siècle adventure narratives to the major works of High Modernism.

This thesis explores prostasomes and their ability to be used as a new diagnostic tool for prostate cancer. Alongside diagnosis, this thesis also suggests prostasomes as a tool for prognosis and therapeutic treatment in patients with prostate cancer.

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Photochemical energy conversion into solar fuel involves steps of light absorption, charge separation and catalysis. Nature has taught us that the effective accumulation of redox equivalents and charge separation are the key steps in sunlight conversion. The focus of this thesis is to unveil photophysical and photochemical processes that lead to accumulative charge separation.

This book examines some central arguments in the debate about the value of death.

This thesis adds to previous work on significant but less pronounced key features for successful organization of primary diabetes care, and indicates that the complexity of diabetes disease makes it difficult to identify success factors applicable to all people living with T2DM.

In this thesis I aim to comprehensively characterize and quantify genetic variation in a natural system, the songbird genus Corvus.

Biologi: Mikrobiologi

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In this thesis, we used proteomics to identify the major excretory-secretory products (ESPs) released by Giardia trophozoites of the WB and GS isolates during interaction with intestinal epithelial cells (IECs) in vitro (Paper I).

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The overall aim was to gather data about pre- and postsurgical factors of importance and long-term outcomes to improve standards of care. Another aim was to explore the expression of somatostatin receptor (SSTR) subtypes and mTOR pathway markers.

The field of two-dimensional (2D) layered materials provides a new platform for studying diverse physical phenomena that are scientifically interesting and relevant for technological applications. Novel applications in electronics and energy storage harness the unique electronic, optical, and mechanical properties of 2D materials for design of crucial components.

The overall aim of the thesis is to contribute with new and deepened knowledge about the teaching and learning of craft when the crafting activity is considered as environmental and sustainability education (ESE).

This thesis aims to develop an epistemology of rhetoric in light of the apparent contemporary post-truth condition of society. Epistemology is hereby understood as concerned with principles for knowledge production within the academic discipline of rhetoric, as well as with an understanding of knowledge production in the public realm.

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Titel: "Metabolic health and cognitive function: the roles of lifestyle and shift work"

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Disputation Per Fors, avd Industriell teknik, "Problemazing Sustainable ICT". Opponent: Professor Saara Taalas, Linnéuniversitetet.

Disputation Sabina Huc, "Moisture induced strains and stresses in Wood". Opponent Professor Sigurdur Ormarsson, Linnéuniversitetet.

(OBS! En lördag)

If only I could sleep – maybe, I could remember